Tibolone is a hormone replacement therapy (HRT) commonly prescribed to relieve menopausal symptoms and help prevent osteoporosis. While many postmenopausal women can safely use tibolone, the NHS warns that certain individuals should consult their doctor before starting treatment.
Specifically, the NHS identifies 12 key groups who need medical guidance prior to taking tibolone. These include women experiencing unexplained vaginal bleeding, those diagnosed with porphyria, and individuals with excessive thickening of the womb lining. Additional groups advised to seek medical advice encompass those with various health conditions or on certain medications.
According to NHS guidance, “Tibolone works by restoring hormone levels and can help prevent bone thinning after menopause. It acts similarly to combined HRT containing oestrogen and progestogen, although it may not increase oestrogen levels as much.” Tibolone is intended for women who have been postmenopausal for over a year. However, women who have had their ovaries removed or are taking gonadorelin analogues may start tibolone immediately.
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Importantly, anyone taking other medications, including herbal treatments, vitamins, or supplements, should consult a healthcare professional before using tibolone. The NHS emphasizes that herbal remedies are not routinely tested for interactions with prescription medicines and may affect how other drugs work.
Tibolone is prescription-only and comes in tablet form, usually taken once daily. Symptom improvement can take up to three months. Common side effects include breast tenderness, vaginal irritation, and abdominal pain, but these often subside within the first few months.
Always follow your doctor’s advice and discuss any concerns before starting tibolone.